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	Provedor de dados BJMBR (1) Autor Andersen,M.L. (1) Bignotto,M. (1) Tufik,S. (1) Palavra-chave Dopamine (1) Genital reflexes (1) Paradoxical sleep deprivation (1) Progesterone (1) Sildenafil (1) Testosterone (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2007 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Effect of sildenafil (Viagra®) on the genital reflexes of paradoxical sleep-deprived male rats BJMBR Andersen,M.L.; Bignotto,M.; Tufik,S.. Since there is evidence that paradoxical sleep deprivation (PSD) elicits penile erection (PE) and ejaculation (EJ), and that the erectile response of rats is mediated by nitric oxide, the present study sought to extend the latter finding by assessing the effects of sildenafil on the genital reflexes of male Wistar rats subjected to PSD. We also determined the influence of sildenafil on hormone concentrations. In the first experiment, sildenafil at doses ranging from 0.08 to 0.32 mg/kg was administered intraperitoneally to rats that had been deprived of sleep for 4 days and to home cage controls (N = 8-10/group). The frequency of PE and EJ was measured for 60 min. PSD alone induced PE in 50% of the animals; however, a single injection of sildenafil did not... Tipo: Info:eu-repo/semantics/article Palavras-chave: Paradoxical sleep deprivation; Sildenafil; Genital reflexes; Dopamine; Testosterone; Progesterone. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001100008 Registros recuperados: 1 Primeira ... 1 ... Última

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